Urolithin B and C act as epigenetic modulators. They have been shown to inhibit HAT activity, which has been associated with their anti-inflammatory properties.
Urolithins also downregulate COX-2, lowering prostaglandin production and inflammation.
References
- Bultman SJ.Interplay between diet, gut microbiota, epigenetic events, and colorectal cancer. Mol Nutr Food Res. 2017;61(1):1500902. Doi: 1002/mnfr.201500902 (Review)
- Hullar MA, Fu BC. Diet, the gut microbiome, and epigenetics.Cancer J. 2014;20(3):170. Doi: 10.1097/PPO.0000000000000053 (Review)